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What Causes Aging?

Four Reasons Aging Leads to Death

There is little mystery that all of us are alive today for explainable reasons. We need air to breathe, food to eat, water to drink, exercise to strengthen, and nutrition to grow. If we do without any of these critical items for too long our survival ranges from the very difficult to the impossible.

And did you know?

We age and die for explainable reasons as well. This fact seems to surprise most people. It shouldn’t. And that’s why Asher Longevity Institute is here to help. At ALI, we have sought to understand the primary causes of death from aging. Because the more we know, the more we can do to extend the quality and quantity (in years) of people’s lives. So, let’s take a closer look at how aging and death are related.

Reason #1 – Our Bodies Lose the Ability to Cleanse Themselves

The fancy term is autophagy, which in Greek literally means to “eat oneself”, and it is a necessary biological function that unfortunately degrades as we become older.

Why autophagy matters

It turns out our bodies are in constant need of cleansing out cells that are still functioning, but have lost their ability to divide (e.g. regenerate.) We call them senescent cells, and although the science behind it can be complex the repercussions are quite simple: Our body’s inability to eat (e.g. cleanse and purge) senescent cells contributes to many of the diseases associated with aging.


One place to look is a favorite seafood delicacy, the lobster. It turns out that lobsters don’t have limits to cell reproduction like us humans. By better understanding why that is, scientific studies begin to shine a bright light on ways to extend that same capability to us humans, including drugs and supplements. Solution Overview – Senolytic Activator and Ageless Cell supplements

Reason #2 – Too Much of a Good Thing in Our Cells is Not Always a Good Thing

Let’s get to know another fancy-sounding term here – mTor. No, mTor is not an Avengers’ character. It is short for “mammalian target of rapamycin (mTOR). This helpful protein plays a significant role in controlling cell behavior. At its most basic level, mTOR is a protein that helps regulate cell growth when we are younger, and serves as an important controller of cell metabolism, growth, and survival as we become older. It’s what helps turn each of us from an infant into a child, from a child into a teenager, and from a teenager into an adult.

Why mTOR matters

It turns out that over-stimulation of the mTor signaling pathway has been shown to play a significant role in diseases such as cancer and Type-2 diabetes. What is good to help grow us is not always good to help what’s growing in us.


If we can “suppress” the over-stimulation of the mTor protein, then diseases related to aging stand less of a chance to develop. mTor suppression is already playing a significant role in the treatment of solid tumors, organ transplants, coronary restenosis (the reduction of artery diameter again after surgery), and rheumatoid arthritis. Solution Overview – Metformin (a drug often used to control high blood sugar), periodic fasting, AMPK supplement and Longevity AI supplement.

Reason #3 – An Essential Protein for Proper Cell Function is Almost Gone by Age 80

Ok, time to get our biology book out again. This one is called NAD+, which is an easier way to remember “nicotinamide adenine dinucleotide”. NAD+ is a co-enzyme (protein catalyst) that is essential for cell function, DNA repair and systemic life sustenance.

Why NAD+ matters

Unfortunately for humans, NAD+ generally declines gradually, about 4% per year, until it is almost absent in our bodies by age 80.


Studies of mice and actual use by humans have shown that reintroducing NAD+ improved cell functioning at the basic level and restored other bodily functions. Solution Overview – NAD+ infusions and supplements

Reason #4 – A Compromised Immune System

It should be no surprise that a strong immune system helps to keep a person healthy. Consisting of organs, cells, tissues, and proteins, your immune system carries out bodily processes that fight off viruses, bacteria, and foreign bodies that cause infection or disease. When this system isn’t working properly, we call it immune dysregulation.

Why immune dysregulation matters

Immune dysregulations is the fundamental cause for diseases in younger adults like severe allergies, Irritable Bowel Syndrome, and hypertension in pregnant women. And as we become older, overreactive immune systems become even more common and are associated with other age-compromising diseases including vasculitis, rheumatoid arthritis, and more.


It is becoming clear that as we age, our cells become stuck in longer-lived response states which means the immune system responses are no longer proportional to the actions needed to combat the threat to the body. Boosting your immune system with proper supplements is one clear way to reduce the negative effects of aging. Solution Overview – Florassist GI probiotic and Immune senescence supplements

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All information and recommendations on this site are for information only and are not intended as formal medical advice from your physician or other health care professionals. This information is also not intended as a substitute for information contained on any product label or packaging. Diagnosis and treatment of any health issues, use of any prescription medications, and any forms of medical treatments should not be altered by any information on this site without confirmation by your medical team. Any diet, exercise, or supplement program could have dangerous side effects if you have certain medical conditions; consult with your healthcare providers before making any change to your longevity lifestyle if you suspect you have a health problem. Do not stop taking any medication without consulting with the prescribing doctor.